A new road to induce heme oxygenase-1 expression by carbon monoxide.

نویسندگان

  • Hong Pyo Kim
  • Augustine M K Choi
چکیده

A New Road to Induce Heme Oxygenase-1 Expression by Carbon Monoxide Print ISSN: 0009-7330. Online ISSN: 1524-4571 Copyright © 2007 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation Research doi: 10.1161/CIRCRESAHA.107.164046 2007;101:862-864 Circ Res. http://circres.ahajournals.org/content/101/9/862 World Wide Web at: The online version of this article, along with updated information and services, is located on the

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Carbon Monoxide Protects against Liver Failure through Nitric Oxide–induced Heme Oxygenase 1

Carbon monoxide (CO) and nitric oxide (NO) each have mechanistically unique roles in various inflammatory disorders. Although it is known that CO can induce production of NO and that NO can induce expression of the cytoprotective enzyme heme oxygenase 1 (HO-1), there is no information whether the protective effect of CO ever requires NO production or whether either gas must induce expression of...

متن کامل

Differential effects of volatile anesthetics on hepatic heme oxygenase-1 expression in the rat.

THE microsomal enzyme heme oxygenase (HO; EC 1.14.99.3) catalyzes the oxidation of heme to biliverdinIXa, iron, and carbon monoxide. So far, three isoforms of this enzyme have been cloned. While HO-2 and HO-3 are constitutively expressed, HO-1 is highly inducible in response to a variety of stimuli and has been identified as the major 32-kd heat shock (stress) protein (HSP) 32. Heme oxygenase–1...

متن کامل

New light on the anti-colitic actions of therapeutic aminosalicylates: the role of heme oxygenase.

Although a variety of pharmaceutical preparations of aminosalicylate are commonly used in the clinic for the control of inflammatory bowel disease, the mechanisms underlying their therapeutic actions remain unclear. Recent in vivo and in vitro studies have demonstrated that 5-aminosalicylic acid (5-ASA), regarded as the active moiety in aminosalicylate preparations such as sulfasalazine, can in...

متن کامل

Induction of Heme Oxygenase -1 By Lipocalin 2 Mediated By Nf-Kb Transcription Factor

Purpose: Effect of lipocalin 2 on the expression of heme oxygenase I , II and NF-kB transcription factor was the purpose of this survey. Materials and Methods: Lcn2 was cloned to pcDNA3.1 plasmid by using genetic engineering method. The recombinant vector was transfected to CHO and HEK293T to establish stable cell expressing lipocalin 2. The presence of lipocalin 2 gene in these cells was confi...

متن کامل

The Expression of Heme Oxygenase-1 in Human-Derived Cancer Cell Lines

Background: Heme oxygenase-1 (HO-1) is a cytoprotective and antiapoptotic enzyme, which has been involved in maintaining cellular homeostasis, and plays an important protective role by modulating oxidative injury. Up-regulation of (HO-1) has contributed to tumorogenicity of some cancers. In this study we investigated the expression pattern of the HO-1, in five different human-derived cancer cel...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:
  • Circulation research

دوره 101 9  شماره 

صفحات  -

تاریخ انتشار 2007